What's New in Atopic Dermatitis Management, With April Armstrong, MD, MPH

The atopic dermatitis treatment landscape is evolving at an unprecedented pace, according to April W. Armstrong, MD, MPH, of UCLA's David Geffen School of Medicine, and those working in the field are working to keep up.

2026 American Academy of Dermatology (AAD) Annual Meeting

 in Denver, Colorado, Armstrong spoke about various key developments spanning long-term safety data, emerging mechanisms of action, and the increasing role of personalized treatment strategies in the moderate-to-severe atopic dermatitis space.

“Some of the things that I highlighted in my session included long-term data for the FDA-approved therapies, both in the biologic realm as well as oral JAK inhibitors,” Armstrong expressed.

On the topic of safety data, Armstrong provided reassurance related to oral Janus kinase (JAK) inhibitors. She noted long-term findings show rates of serious infections and major adverse cardiovascular events (MACE) in the atopic dermatitis population appear to be comparable to background rates seen in patients with moderate-to-severe disease. With this in mind, Armstrong stressed the value of Zoster vaccination prior to, or concurrent with, beginning oral JAK inhibitor treatment, given the link to elevated risk of Zoster infection.

Later in the interview, Armstrong turned her attention to the drug pipeline, touching on the wave of innovations seen across both familiar and novel therapeutic pathways. Longer-term data were noted as currently available for agents targeting the OX40 ligand pathway. Newer approaches are also exploring more precise inhibition of the interleukin (IL)-4 receptor alpha.

Outside of biologics, Armstrong also spoke about oral drugs targeting STAT6, as opposed to JAK molecules, emerging as noteworthy in dermatology. She also pointed to the growing interest in bi-specific and tri-specific molecules designed to simultaneously inhibit multiple targets, an approach aimed at addressing the heterogeneity of disease presentations.

Despite the momentum, Armstrong later described the management of moderate-to-severe atopic dermatitis as continuing to be a highly individualized challenge. For individuals with refractory disease, she encouraged clinicians in the field not to be discouraged, emphasizing combination therapy as potentially appropriate for certain patients.

The quotes used in this video summary were edited for clarity.

Armstrong has served as a consultant for and received honoraria from AbbVie, Almirall, Arcutis, ASLAN, Beiersdorf, Boehringer Ingelheim, Bristol Myers Squibb, Dermavant, Dermira, EPI, Incyte, Janssen, LEO Pharma, Eli Lilly, Nimbus, Novartis, Ortho Dermatologics, Pfizer, Regeneron, Sanofi, Sun, and UCB and has participated in advisory boards for Boehringer Ingelheim and Parexel.

Armstrong A, et al. S065 What's New in Dermatology. Session presented at: 2026 American Academy of Dermatology Annual Meeting; March 27–31, 2026; Denver, CO.

Armstrong AW, Rubin C, Jarell A, et al. Real-world effectiveness of 12 months tralokinumab treatment in patients with skin of color and moderate-to-severe atopic dermatitis: final data from the prospective, non-interventional, international TRACE study. Presented at the 2026 American Academy of Dermatology Annual Meeting; March 27-31, 2026; Denver, CO. Poster ID: 77199. Oral Poster Presentation.

Videos

At AAD, April W. Armstrong, MD, MPH, discussed recent innovations in the atopic dermatitis treatment space, highlighting long-term safety data and more.

Atopic Dermatitis

Atopic Dermatitis condition center page, audiences can find a variety of coverage mediums for medical news and updates, including articles, video interviews, podcasts, and breaking news on dermatitis research, treatment, and drug development.

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Nancy Reau, MD, is Professor of Internal Medicine, Richard B. Capps Chair of Hepatology, Associate Director of Solid Organ Transplantation, and Section Chief of Hepatology at Rush University Medical Center.

Kimberly Brown, MD, is division chief of gastroenterology and hepatology and the Associate Medical Director of the Henry Ford Hospital Transplant Institute at Henry Ford Hospital. She is also a Professor of Medicine at Wayne State University

Meena Bansal, MD, is director of the MASLD/MASH (NAFLD/NASH) Center of Excellence at Mount Sinai and System Chief, Division of Liver Diseases for the Mount Sinai Health System.

PCOS, Pregnancy, and MASLD Risk: What Clinicians Need to Know

metabolic dysfunction-associated steatotic liver disease (MASLD)

 continues to grow, increasing attention is being paid to how reproductive and metabolic conditions uniquely shape risk in women. Among these, 

 and pregnancy represent critical but often underrecognized periods where hormonal and metabolic factors intersect to influence liver health.

In this segment from a recent episode of 

Liver Lineup: Updates and Unfiltered Insights

, Meena Bansal, MD, joins hosts Nancy Reau, MD, and Kimberly Brown, MD, to examine the complex relationship between PCOS, pregnancy, and MASLD.

Bansal emphasizes that PCOS is a well-established risk factor for MASLD and its more advanced form, MASH, largely driven by underlying insulin resistance. While the condition is widely recognized in endocrinology, its implications for liver health are often underappreciated. She notes that patients with PCOS should be evaluated for liver fibrosis using noninvasive tools, and those with evidence of stage 2 or 3 fibrosis may be appropriate candidates for currently approved therapies.

The discussion then shifts to pregnancy as a critical period of risk. Women entering pregnancy with metabolic comorbidities such as obesity or diabetes may already be predisposed to MASLD, and the physiologic changes of pregnancy, including weight gain, can further exacerbate disease progression. According to Bansal, emerging data suggest that MASLD during pregnancy is associated with increased risks of adverse maternal outcomes, including gestational diabetes and preeclampsia, as well as complications for the fetus, such as preterm birth and abnormal growth patterns.

The conversation also touches on the potential for long-term, intergenerational effects. Bansal highlights research suggesting that maternal metabolic health may influence fetal outcomes through epigenetic mechanisms, potentially increasing a child’s lifetime risk of metabolic disease and liver dysfunction. While she says these findings require further validation, they underscore the broader implications of MASLD beyond the individual patient.

Reau and Brown further explore how current therapies fit into this landscape, particularly for younger, premenopausal women. Although GLP-1 receptor agonists have shown benefits in weight loss and metabolic regulation and may even improve menstrual regularity in some patients with PCOS, their use is contraindicated during pregnancy. Bansal points out the challenges this creates in preconception care, including uncertainty around weight regain after discontinuation and its potential impact during pregnancy.

As Bansal notes, more research is needed to better understand how to tailor care for women with MASLD, especially during periods of hormonal and metabolic transition.

Editors’ note: Relevant disclosures for 

 include AbbVie, Gilead, Salix, Arbutus, and VIR. Relevant disclosures for 

 include Mallinckrodt Pharmaceuticals, Gilead, Salix, Intercept, Ipsen, and Madrigal. Relevant disclosures for 

 include Boeheringer-Ingelheim, Boston Pharma, Fibronostics, GSK, Madrigal, Merck, NOVO Nordisk, and The Kinetix Group.

DiStefano JK. NAFLD and NASH in Postmenopausal Women: Implications for Diagnosis and Treatment. Endocrinology. 2020;161(10):bqaa134. doi:10.1210/endocr/bqaa134

Sarkar M, Kushner T. Metabolic dysfunction-associated steatotic liver disease and pregnancy. J Clin Invest. 2025;135(10):e186426. Published 2025 May 15. doi:10.1172/JCI186426

Mass General Brigham. Patients Who Discontinued GLP-1s Had More Weight Gain, Complications During Pregnancy. November 24, 2025. Accessed April 17, 2026. 

https://www.massgeneralbrigham.org/en/about/newsroom/press-releases/pregnancy-effects-from-discontinued-glp-1-use

Experts discuss how metabolic and hormonal factors in women influence MASLD risk, progression, and potential long-term outcomes.

Endocrinology

The HCPLive endocrinology page is a comprehensive resource for clinical news and insights on endocrine system conditions. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for diabetes, hormonal disease, and more.

Hepatology

Polycystic Ovary Syndrome

MASH / MASLD

The HCPLive MASH & MASLD page is a comprehensive resource for clinical news and insights on metabolic dysfunction-associated steatotic liver disease and steatohepatitis. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for fatty liver disease, steatohepatitis, and more.

MASLD and Women’s Health: The Roles of PCOS and Pregnancy

Roy Beck, MD, PhD, is the founder of the Jaeb Center for Health Research.

INHALE-3 Analysis Supports Need for Increased Technosphere Insulin Doses, With Roy Beck, MD, PhD

Technosphere insulin (TI), an ultrarapid-acting inhaled insulin, has shown its efficacy in glucose management in higher doses than have been approved for adults with 

, according to an analysis from INHALE-3.

“One of the challenges that we have in treating patients with injectable insulin is that it’s injected underneath the skin,” Roy Beck, MD, PhD, founder of the Jaeb Center for Health Research, told 

 in an exclusive interview. “It takes some time to be absorbed into the bloodstream, and so there’s a delay much greater than what we see with a pancreas producing insulin normally. When insulin is inhaled and goes into the lung, it distributes into the bloodstream very rapidly and becomes something very close to endogenous insulin.”

TI is the first and only ultrarapid-acting inhaled insulin to receive approval from the 

 for the improvement of glycemic control in patients with diabetes mellitus. Initially approved under the brand name Afrezza, TI received an update to its prescribing information on January 26, 2026, revising the recommendations for starting mealtime dosage when patients switch from subcutaneous mealtime insulin regimens.

INHALE-3 was a multicenter, randomized, controlled study comparing the safety and efficacy of TI combined with insulin degludec versus standard care in adults with T1D. This latter group included treatment regimens of multiple daily injections or insulin pump therapy, including automated insulin delivery (AID) systems. Patients were not blinded to treatment.

Upon randomization, patients in the TI treatment arm transitioned from their previous insulin therapy using a conversion ratio modified from existing recommendations, wherein the TI dose is calculated by multiplying the patient’s usual subcutaneous rapid-acting insulin analogue (RAA) dose by 2 and rounding down to the nearest available cartridge size from among 4, 8, or 12 U, or a combination thereof. The first dose of TI was administered in-clinic, after which patients were instructed to titrate their TI dose over time based on glucose response.

The present analysis analyzed a specific subgroup of patients who had been randomized to the T1D and degludec arm and had complete insulin dosing data at all 3 key timepoints – baseline, week 17, and week 30. Patients were eligible for inclusion if they had non-missing data for total daily insulin doses and mealtime dosing at each time point. A total of 35 patients from INHALE-3 met these criteria and were included.

Among these patients, the mean age was 46 years with a baseline A1c of 7.72% (standard deviation [SD] +/- 1; 61 mmol/mol). Prior to TI initiation, 40% of participants were using AID. The mean baseline bolus and basal dose of RAA insulin were 23.9 U/d, with a bolus/basal ratio of roughly 50%/50%. After 30 weeks of monitoring, mean total daily TI dose increased from 36 U at baseline to 48 U at 17 weeks (

 <.001). By 30 weeks, the TI bolus/basal ratio had also shifted to around 70%/30% (

 <.001). At 17 weeks, 57% of participants had increased their TI dose by >4 U, which then increased to 74% at 30 weeks. Notably, investigators recorded no new safety signals with TI treatment.

Given these data, the FDA’s approval of higher starting doses for TI is no surprise. Investigators did, however, emphasize that higher overall dosing requirements are needed to support individualized titration and help patients reach their glycemic goals.

“All patients could potentially improve with this, because everyone who has diabetes has the potential for a spike after they eat,” Beck said. “There’s a real benefit to trying to reduce that by getting insulin into the bloodstream faster, although the effect of that insulin goes away pretty quickly. There were a substantial proportion of participants who improved quite a bit, but there were some who didn’t, and I think it’s largely because it took a certain regimented approach to frequent inhaling if your glucose was still high.”

Editors’ Note: Beck reports that his institution has received funding on his behalf from Insulet, Tandem Diabetes Care, Beta Bionics, Abbott, Dexcom, Sequel Med Tech, and others.

Rittenberry J, Sylvan J, Mycue L-E, Griparic L, Kaiserman K. Inhaled insulin dosing in a randomized trial in adults with type 1 diabetes. 

MannKind Corporation. MannKind Announces FDA Approval of Updated Afrezza Label Providing Starting Dose Guidance when Switching from Multiple Daily Injections (MDI) or Insulin Pump Mealtime Therapy. January 26, 2026. Accessed April 17, 2026. 

https://investors.mannkindcorp.com/news-releases/news-release-details/mannkind-announces-fda-approval-updated-afrezzar-label-providing

Beck discusses a recent analysis of the phase 4 trial comparing TI and degludec against standard treatment, highlighting the need for individualized titration.

Type 1 Diabetes

Marie-José van Tol, PhD, from the University of Groningen.

Preventive Therapy Targeting Positive Affect May Reduce MDD Relapse, With Marie-José van Tol, PhD

New findings suggest preventive cognitive therapy (PCT) may lower relapse risk in remitted recurrent 

by improving pleasure and modifying dysfunctional attitudes.

, Marie-José van Tol, PhD, from the University of Groningen, discussed new data examining the cognitive and affective mechanisms underlying preventive cognitive therapy (PCT), highlighting the role of positive affect and anhedonia in reducing relapse risk.

“In order to change dysfunctional attitudes that are very quite rigid and related to depressive relapse, we need to also focus on increasing the ability to experience pleasure and to up regulate positive emotions,” van Tol said.

The study included 69 unmedicated individuals with remitted MDD at high risk for recurrence from the NEWPRIDE randomized controlled trial. The findings showed a 3-month PCT intervention directly improved consummatory pleasure, the inverse of anhedonia, and increased use of cognitive reappraisal, which together contributed to reductions in dysfunctional attitudes associated with relapse vulnerability. Change in anhedonia (odds ratio [OR], 0.79; 95% CI, 0.68–0.92; 

 =.003] and dysfunctional attitudes (OR, 0.93; 95% CI, 0.86–0.99; 

 =.041) predicted relapse status at 18-month follow-up in PCT-recipients.

The analysis demonstrated that improvements in pleasure mediated the relationship between PCT and reductions in maladaptive beliefs (P =.003). Van Tol described this as a “cross-valence” mechanism, in which strengthening positive affective experiences may buffer against the impact of negative life events.

“It seems that if we focus on improving the ability to have positive feelings, this might lower the impact that negative events have on us, and thereby also lower the impact it has on an individual, and thereby de-learning, in a sense, these negative beliefs about yourself,” she said.

The study focused on unmedicated individuals, but van Tol noted prior evidence suggests PCT may also provide benefit when combined with maintenance antidepressant therapy. She added that the observed mechanisms involving positive affect require further validation in broader populations.

From a practical standpoint, van Tol suggested clinicians consider incorporating strategies that actively promote positive emotional experiences alongside traditional cognitive techniques. These approaches may include encouraging engagement in rewarding activities, fostering savoring of positive experiences, and strengthening emotion regulation skills through reinterpretation of situations. She said these interventions may improve resilience and reduce vulnerability to recurrence.

Although cognitive reappraisal improved following PCT, it did not independently predict relapse in this study. Van Tol indicated that reappraisal likely contributes as part of a broader set of skills rather than as a standalone therapeutic target.

“Focusing on improving a reappraisal probably will not be enough,” van Tol said.

Angeles-Valdez D, van Kleef R, van Valen E, Garza-Villarreal EA, Bockting C, van Tol MJ. The role of cognitive and affective changes in preventing depressive relapse: A network analysis approach to understanding the mechanisms of preventive cognitive therapy. 

Research suggests preventive cognitive therapy reduced relapse risk in recurrent depression by improving positive affect and anhedonia, van Tol explained in an interview.

Psychiatry

Psychiatry condition center page is a comprehensive resource for clinical news and insights on mental illnesses. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for depression, schizophrenia, bipolar disorder, anxiety, and more.

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Major Depressive Disorder condition center page, resources on the topics of medical news and expert insight into depression can be found. Content includes articles, interviews, videos, podcasts, and breaking news on MDD research, treatment, and drug development.

One-Time Gene-Editing Therapy Gives Patients “Freedom” From Pain Crisis

An experimental one-time gene-editing cell therapy may have the potential to give patients with 

 “freedom” from frequent medical interventions and pain crises.

According to findings, 27 out of 28 patients treated with renizgamglogene autogedtemcel (reni-cel) did not report any severe vaso-occlusive events after infusion.

nephrology team spoke with the lead author and chair of the Pediatric Hematology – Oncology & Blood and Bone Marrow Transplant Division at Cleveland Clinic Children’s, Rabi Hanna, MD, to discuss how meaningful this data is for this patient population.

“It is not only enough to survive—it is important to thrive for these patients. That’s why, in addition to this, we are excited to report and collect patient-reported outcomes,” Hanna shared. “And we can see, as we shared during ASH, that patient fatigue and physical activity are almost back to normal. So they are thriving, not only surviving.”

What Does Reni-Cel Do, and How Did Hanna Investigate It?

Reni-cel is an investigational clustered regularly interspaced short palindromic repeats (CRISPR)–Cas12a gene-edited autologous hematopoietic stem-cell therapy. The novel, autologous technique is designed to modify a patient’s own blood-forming stem cells to correct the mutation responsible for sickle cell disease, increasing fetal hemoglobin levels to prevent red blood cells from forming into sickle-shaped cells, and improving overall hemoglobin levels to reduce complications from the disease.

The therapy differs from previously approved therapies, Hanna explains, in 2 key ways. First, it uses Cas12a instead of Cas9, offering increased specificity. Secondly, it mimics a natural process, targeting the HBG1 and HBG2 promoters. This is similar to what occurs in individuals with sickle cell disease who remain asymptomatic due to persistently elevated fetal hemoglobin.

Hanna and colleagues examined this underlying mutation in those individuals and aimed to mimic it in a phase 1-2 multicenter, open-label, single-group study where 28 patients were treated with a single infusion of renicel after myeloblative conditioning with busulfan, a high-dose chemotherapy regimen used before allogeneic stem cell transplantation (HCT) to eliminate cancer cells and suppress the immune system.

What Did Investigators See With Reni-Cel-Treated Patients?

According to the results, among 27 patients who had neutrophil and platelet engraftment by the data-cutoff date, neutrophil engraftment, the process where transplanted stem cells begin producing new, healthy blood cells in a patient's bone marrow. occurred after a median of 23 days (range, 14 to 29). Additionally, platelet engraftment, the process where newly transplanted stem cells begin producing platelets, signaling recovery in hematopoietic stem cell transplants, occurred after a median of 25 days (range, 17 to 51).

At month 6, among 18 patients with at least 6 months of available data, the mean (±SD) total hemoglobin level (9.8±1.7 g per deciliter at baseline) had increased to 13.8±1.9 g per deciliter, and the mean percentage of fetal hemoglobin (2.5±2.5% at baseline) had increased to 48.1±3.2%. Both of these measures remained stable.

In terms of pain crisis, 1 patient had 2 severe vaso-occlusive events after infusion. Overall, the adverse events were consistent with those that occur after myeloablative busulfan-based conditioning and autologous hematopoietic stem-cell transplantation.

“Think of the days this is giving them back now. Even in the one patient who did have pain, that patient previously had 6 to 7 pain crises per year and had only 1 event after treatment, in the setting of infection. This is very promising data, and we will continue to follow these patients long term, including pain outcomes and, importantly, organ effects.”

Hanna further notes anecdotal data of improvement in vasculopathy or pulmonary hypertension, remarking that these metrics warrant further study. Additionally, he emphasizes that, given reni-cel is an innovative therapy, investigators will need to continue to monitor for any potential long-term side effects.

Editor’s Note: Hanna reports relevant disclosures with Chiesi USA, Inc., Swedish Orphan Biovitrum AB (Sobi), and Vertex Pharmaceuticals Incorporated.

Hanna R, Frangoul H, Pineiro L, et al. CRISPR-Cas12a Gene Editing of 

 Promoters to Treat Sickle Cell Disease. 

Popat UR, Pasvolsky O, Bassett Jr. R, et al. Myeloablative fractionated busulfan for allogeneic stem cell transplant in older patients or patients with comorbidities. 

https://doi.org/10.1182/bloodadvances.2023010850

Hanna describes the "freedom" patients with sickle cell disease reported after being treated with reni-cel, a one-time edited gene therapy. 

Hematology

Sickle Cell

Sickle Cell condition center page, resources on the topics of medical news and expert insight into sickle cell disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on sickle cell research, treatment, and drug development.

Strategic Alliance Partnership

Abigail Brooks is an assistant managing editor for 

She joined MJH Life Sciences in August 2023 shortly after graduating from Monmouth University where she earned her BA in Communication with a concentration in Public Relations/Journalism and later an MA in Interactive Digital Media. She enjoys traveling, running, and reading books. She can be reached at abrooks@mjhlifesciences.com.

Articles

View slated expert interviews and 7 clinical trials to watch at AACE Annual Meeting 2026.

Obesity Management

Obesity Management condition center page, resources on the topics of medical news and expert insight into clinical weight management can be found. Content includes articles, interviews, videos, podcasts, and breaking news on obesity research, treatment, and drug development.

AACE Annual Meeting 2026 Preview: 7 Trials to Know

Silvia Mariel Ferrucci, MD, is an adjunct professor of dermatology at the University of Milan and the head of the the Allergology Dermatology Service at Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico.

In this Q&A interview, Ferrucci highlights key real-world findings from the GLOBOSTAD on the safety and efficacy of dupilumab (Dupixent) in atopic dermatitis.

GLOBOSTAD: 3 Year Efficacy of Dupilumab in Atopic Dermatitis, With Silvia Mariel Ferrucci, MD

Phillip Levy is an Assistant Professor of Emergency Medicine and Assistant Professor of Physiology at Wayne State University and the Assistant Vice President for Research at Wayne State University Department of Emergency Medicine.

Data from a study deploying mobile health units across Detroit, Michigan, found CKD stage ≥3 rates double the national average and increased rates in at-risk subgroups.


Nephrology

The HCPLive nephrology page is a resource for medical news and expert insights on kidney disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments in nephrology, and more.

Chronic Kidney Disease

This City’s CKD Stage ≥ 3 Incidence is Double The US National Average

Blauvelt discusses studies revealing that disease severity, injection frequency, pain, and geography all shape treatment preferences.



Plaque Psoriasis

The HCPLive plaque psoriasis page is a resource for medical news and expert insights on psoriasis. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for psoriatic disease, and more.

Dermatology

The HCPLive dermatology page is a resource for medical news and expert insights on skin disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for dermatologic conditions, and more.

Understanding Patient Preferences in Psoriasis, With Andrew Blauvelt, MD, MBA

Armstrong highlights several major takeaways from her portion of the AAD 2026 session titled 'IL-23 Innovation: New Data Addressing Plaque Psoriasis.'

Highlighting Key IL-23 Innovations in Dermatology, With April W. Armstrong, MD, MPH

Diana Isaacs, PharmD, is an endocrine clinical pharmacist, director of Education and Training in Diabetes Technology, and codirector of Endocrine Disorders in Pregnancy at the Cleveland Clinic.

Podcasts

This episode explores the launch and accessibility of FDA-approved oral GLP-1 orforglipron, including availability through Amazon Pharmacy's same-day delivery service.

FDA News

Diabetes Dialogue

Diabetes Dialogue: Technology, Therapeutics, & Real-World Perspectives is a monthly podcast hosted by Diana Isaacs, PharmD, and Natalie Bellini, DNP, aimed at providing a regular roundup of the latest clinically applicable insights across diabetes and metabolic diseases, with a focus on leveraging technology to improve care.

podcasts page features a feed of medical news and interview podcast series, including DocTalk, Lungcast, Derm Discussions, and Heart Trials.

Diabetes Dialogue: Orforglipron Availability, Amazon Pharmacy, and Dosing Considerations

Vaiibhav Patel, MD, is a cardiologist at the Ohio State University Wexner Medical Center.

Patel provides an inside perspective on one of the most diagnostically challenging cardiovascular conditions.

Cardiology

Cardiology condition center page is a comprehensive resource for clinical news and insights on cardiovascular and cardiometabolic diseases. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for heart disease and cardiovascular events, as well as associated diabetes, renal failure, and more...

The Current Diagnostic and Treatment Landscape of Cardiac Sarcoidosis, With Vaiibhav Patel, MD

Hosts are joined by Meena Bansal, MD, to discuss long-standing research gaps and what clinicians need to understand about sex-specific drivers of liver disease today.

Liver Lineup: Updates & Unfiltered Insights

Introducing Liver Lineup: Updates & Unfiltered Insights — an exciting new podcast delivering timely, candid perspectives on the most pressing topics in the fast-moving world of hepatology. Created by Nancy Reau, MD, and Kimberly Brown, MD, and hosted by HCPLive, this series dives into the cutting edge of liver disease research, clinical care, and real-world practice.

Liver Lineup: Closing the Gap in Women’s Liver Health

James Murrough, MD, PhD, from the Icahn School of Medicine at Mount Sinai.

Murrough discusses ADAA 2026 findings evaluating azetukalner in MDD with anhedonia; exploratory outcomes suggest potential benefit despite nonsignificant primary endpoints.

Kv7 Channel Modulator Shows Promise for Anhedonia in MDD, With James Murrough, MD

Hanna, MD, shares results from reni-cel, a one-time gene editing therapy for patients with sickle cell disease. 

Latest News

What's New in Atopic Dermatitis Management, With April Armstrong, MD, MPH

MASLD and Women’s Health: The Roles of PCOS and Pregnancy

INHALE-3 Analysis Supports Need for Increased Technosphere Insulin Doses, With Roy Beck, MD, PhD

Preventive Therapy Targeting Positive Affect May Reduce MDD Relapse, With Marie-José van Tol, PhD

One-Time Gene-Editing Therapy Gives Patients “Freedom” From Pain Crisis