This systemic inflammatory disorder (also called reactive arthritis) manifests as peripheral arthritis that is sometimes accompanied by such extra-articular findings as urethritis, conjunctivitis, and uveitis. The condition is triggered by infections of the genitourinary or GI tracts, including Chlamydia, Yersinia, Shigella, Salmonella, and Campylobacter infections.1
Several mucocutaneous lesions are typical of Reiter syndrome. Keratoderma blennorrhagicum (A) is a psoriasiform rash, found most commonly on the soles and palms, that histologically resembles a pustular psoriatic lesion. Fingernails may be thickened and opacified but are not pitted (a feature that distinguishes Reiter syndrome from psoriatic arthritis). Circinate balanitis (B) is a painless erythematous lesion of the glans penis that usually has distinct borders. Similar lesions can be found in the buccal mucosa.
1. Amor B. Reiter's syndrome: diagnosis and clinical features. Rheum Dis Clin North Am. 1998;24:677-695.