A healthy 50-year-old woman walks into your office; she is concerned about her risk of breast cancer because right-sided breast cancer was diagnosed in her mother at age 55. She is of Caucasian ancestry and has no other family members with breast, ovarian, or prostate cancer. She has read the news about an actress who had a “cancer gene” and ended up having prophylactic mastectomies. She is very concerned about her risk of developing breast cancer and wants to be “tested.”
With genetic tests rapidly entering medical practice, and some patients even ordering them on their own, the NIH has launched a Genetic Testing Registry to help doctors interpret and follow up on these tests. In this interview, the director of the new Genetic Testing Registry tells why you need it, and what's there for your reference.
A consortium called CPIC has issued a new guideline on genetic tests that can mean the difference between toxic reactions or unrelieved pain for some patients on codeine. Dr. Mary Relling tells why primary care doctors need good information right now about the links between genes and drug response, and where you can find it.