Among the most common causes of infection outside health-care institutions, community-acquired methicillin-resistant Staphylococcus aureus (Community aquired-MRSA) most often affects the skin and soft tissues. Besides causing significant morbidity, community-aquired MRSA is increasingly associated with serious and often fatal necrotizing pneumonia or fasciitis, endocarditis, and sepsis. The authoritative links on this resource help you to keep up to date with new diagnostic tests and treatments for community-aquired MRSA, as well as the latest news about local outbreaks and infection control strategies.
A15-year-old girl was referred to a pediatric endocrinologist for evaluation of hyperthyroidism. Her primary concerns were intermittent increases in heart rate and appetite (with a weight gain of 7 kg within the past year), feeling hot at night even in winter, persistent lower extremity edema that had been present since age 4 years, and difficulty in concentrating. She denied having diarrhea, sweating, fatigue, breathing difficulties, hair loss, or changes in hair texture.
For 3 days, a 7-year-old girl had severe, generalized abdominal pain. The patient described the pain as sharp and achy without radiation; she denied any relieving or aggravating factors. She also reported decreased appetite and energy for the past week.
The rash on this 4-week-old girl had appeared 5 days earlier on her face as thickened scales on an erythematous base and subsequently spread to the scalp, shoulder, chest, abdomen, and extremities. A few bullae were noted on the neck and hands. Initial treatment with cephalexin failed to control the rash, and the infant was admitted to the hospital for further evaluation.
The rash on this 4-week-old girl had appeared 5 days earlier on her face as thickened scales on an erythematous base and subsequently spread to the scalp, shoulder, chest, abdomen, and extremities. A few bullae were noted on the neck and hands. Initial treatment with cephalexin failed to control the rash, and the infant was admitted to the... More »
Septic arthritis and several other types of musculoskeletal infections in children are caused by group A Streptococcus. Methicillin-resistant Staphylococcus aureus is emerging as a cause of skin infections in the sports community. Neisseria meningitidis in purpura fulminans usually is not associated with direct infection of musculoskeletal structures. More »
A novel H1N1 influenza virus has emerged from swine and is causing a worldwide pandemic. Children and young adults have been most affected, in terms of both numbers of cases and severity of disease. Perhaps the most striking feature of the pandemic so far is that fewer than half of those hospitalized or killed by this virus have had identifiable prior medical conditions or risk factors. More »
THAT BLUE LIGHT KILLS methicillin-resistant Staphylococcus aureus (MRSA) was demonstrated in the article “Visible 405 nm SLD Light Photo-Destroys Methicillin-Resistant Staphylococcus aureus (MRSA) In Vitro,” in the December 2008 issue of Lasers in Surgery and Medicine. Concerns about the clinical safety of the wavelength used (405 nm, spectral width 390 to 420 nm), which contains traces of ultraviolet light, led Chukuka Enwemeka, PhD, and colleagues from the School of Health Professions,... More »
Health care–associated pneumonia (HCAP) is a relatively new term used to describe pneumonia that develops in patients who have recently been exposed to nosocomial and drug-resistant pathogens as a result of hospitalization or residence in a nursing home, for example. A recent study found that about 25% of patients hospitalized with pneumonia had HCAP, and that the mortality rate was higher in those with HCAP than in those with community-acquired pneumonia (CAP). More »
I advise my patients who are carriers of methicillin-resistant Staphylococcus aureus (MRSA) to keep their fingernails trimmed. Long nails make the subungual spaces good havens for bacteria. S aureus, including MRSA, has been isolated from the subungual spaces of the hands of many at-risk patients who are MRSA carriers More »
Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor that is usually well tolerated with few adverse effects, but it has been implicated in the development of Fanconi syndrome and renal insufficiency because of its effects on the proximal renal tubule. Vancomycin nephrotoxicity is infrequent but may result from coadministration with other nephrotoxic agents, such as aminoglycosides. We report the cases of 2 patients receiving tenofovir as part of an antiretroviral... More »
A 53-year-old woman with metastatic ovarian cancer presented with excessive tearing of the left eye that was associated with redness and swelling. More »
Infective endocarditis (IE) starts as a vegetation on the valvular structures. The infection can extend to the adjacent periannular areas and erode into nearby cardiac chambers, leading to an aorto-cavitary fistula (ACF).1,2 More »
vancomycin for treatment of complicated skin and soft-tissue infections (cSSTIs) caused by methicillin-resistantStaphylococcusaureus (MRSA). METHODS: Patients with proven MRSA cSSTI were randomized to receive linezolid or vancomycin. ...
(5%) body wash versus standard body wash to prevent colonization with methicillin-resistantStaphylococcusaureus (MRSA) ... (TTO) has been shown to be effective in removing MRSA on the skin. However to date no trials have ...
hospital-acquiredMRSA (6). Almost all community-acquiredMRSA isolates in the United States (but few if any ...community-acquiredMRSA differs from that of MSSA and hospital-acquiredMRSA and that nasal carriage is not the prime predictor of subsequent infection. ...
Zinderman CE Conner B Malakooti MA LaMar JE Armstrong A Bohnker BK. Community-acquiredmethicillin-resistantStaphylococcusaureus... trial of cephalexin for treatment of uncomplicated skin abscesses in a population at risk for community-acquiredmethicillin-resistantStaphylococcusaureus infection. ...
RESEARCH DESIGN: We discuss the example of an ongoing cluster randomized trial to prevent methicillin-resistantStaphylococcusaureus (MRSA) ... screening cultures of ICU admissions followed by Contact Precautions if MRSA-positive (b) screening cultures of ICU admissions followed ...
CONTEXT: Methicillin-resistantStaphylococcusaureus (MRSA) is a pathogen of public health importance; MRSA prevention programs that may affect MRSA... health care settings. Whether there have been changes in MRSA infection incidence as these programs become established is unknown; ...
can lead to blindness molecular studies were conducted to assess the prevalence of methicillin-resistantStaphylococcusaureus (MRSA) ... be S aureus-positive of which only six strains were MRSA. The highest resistance was observed for penicillin ...
Methicillin-resistantStaphylococcusaureus (MRSA) and vancomycin-resistant enterococcus (VRE) have achieved significant rates of colonization and infection ... Both pathogens share common epidemiologic characteristics that suggest similar surveillance and control strategies. MRSA and VRE are readily found on colonized patients and their environment; ...
methicillin-resistantStaphylococcusaureus (MRSA) in total knee arthroplasty (TKA) is becoming a more frequent concern as increased ... reported for infections by resistant organisms. This study investigates whether MRSA infections are associated with decreased functional scores. ...
They have been produced after a literature review of the treatment and prophylaxis of methicillin-resistantStaphylococcusaureus (MRSA). ... published for the antibiotic treatment of common and emerging community-onset MRSA infections in the UK. The guidelines have reviewed ...
Methicillin-resistantStaphylococcusaureus (MRSA) is a bacterium that can colonize or infect people. MRSA strains are not more ... hands of health care workers. Limiting the spread of MRSA is desirable because the organism is resistant to oxacillin nafcillin ...