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4 New Developments in Diabetes

4 New Developments in Diabetes


  • New developments in diabetes you may have missed.

  • The dysfunctional β-cell is the common denominator in all diabetes, regardless of the subtype or category. The author proposes that a β-cell centered schema would be more clinically useful and lead to more optimal patient care. Underutilized treatments could become rational choices to target individual mediating pathways of hyperglycemia.

  • Living with type 2 diabetes tends to increase the risk of depression. Is duration of diabetes a direct or indirect cause of depression in later life? Finding: Living with diabetes for >30 years triples the risk of depression. Frailty could explain some of the association. Strategies that decrease diabetes-related complications also may reduce the risk of depression among older men.

  • Antipsychotics taken for nonpsychotic and off-label indications may raise the risk of cardiometabolic adverse effects, especially type 2 diabetes in young people. Findings: study found that the cumulative risk of T2D was 2.5 times higher in youths who took antipsychotics than in healthy controls. Implications: Antipsychotics should be used judiciously and for the shortest time frame for young patients.

  • Close to 90% of the ~86 million Americans who have prediabetes are unaware that they have the condition. A new joint awareness campaign was launched by the ADA, AMA, CDC, and Ad Council: Type 2 Diabetes Prevention. Includes a real-time 60-second TV commercial prediabetes test and an online 7- question risk test (DoIHavePrediabetes.org.).

This very brief overview of 4 recent developments in type 2 diabetes includes: a call for a new way to classify the disease using dysfunctional β-cells, a link between the duration of depression and diabetes, increased risk of diabetes in young patients with antipsychotics, and a new online test for prediabetes.

 

 

References: 

1. Schwartz SS. The time is right for a new classification system for diabetes: rationale and implications of the B-cell-centric classification schema. Diabetes Care. 2016;39:179-186.

2. Almeida OP, McCaul K, Hankey GJ, et al. Duration of diabetes and its association with depression in later life: The Health In Men Study (HIMS). Maturitas. Published online January 11, 2016.

3. Galling B, Roldán A, Nielsen RE, et al.  Type 2 diabetes mellitus in youth exposed to antipsychotics. JAMA Psychiatry. Published online January 20, 2016.

4. Press release. First-of-its-kind PSA campaign targets the 86 million American adults with prediabetes. American Diabetes Association. January 21, 2016.

Web site: So, do I have prediabetes? Ad Council. DoIHavePrediabetes.org. Accessed February 1, 2016.

Comments

Insulin/glucose metabolism is present in every organ of our body function or functions i.e.neuropathy,arthropathy etc so why not depresion,insomnia,schizophrenia etc.

JUAN @

Insulin dysfunction(beta cells dysf) "causes diabetes in those patience that have predisposition to become diabetics more than "atypical" meds. by themselves doing it. Adding metformin could prevent(???) onset of diabetes besides diet ,weight control,excercising etc. in these kind of patiences

JUAN @

Insulin dysfunction(beta cells dysf) "causes diabetes in those patience that have predisposition to become diabetics more than "atypical" meds. by themselves doing it. Adding metformin could prevent(???) onset of diabetes besides diet ,weight control,excercising etc. in these kind of patiences

JUAN @

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