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Woman with Elevated A1C Who Has Had A Stroke

By Edward Shahady, MD | April 30, 2012
Dr. Shahady is Medical Director of the Diabetes Master Clinician Program, Florida Academy of Family Physicians.

Sue Jones, 79-years-old, has had type 2 diabetes for 15 years. She is home-bound after a recent stroke and now requires assistance with most of her activities. She has a daytime sitter and a weekly visiting nurse; her family provides care in the evenings and on weekends. The family has moderate means and would like to keep her at home. Sue can communicate effectively: she recognizes all of her family members and you, as her physician.

Her most recent lab tests showed an HbA1c of 9.6; a random blood sugar of 450; triglycerides, 350 mg/dL; HDL, 40; LDL, 110 (calculated); total cholesterol, 220; and non-HDL,180.

Some of her medications were stopped when she was discharged from the hospital 3 weeks ago. She now only takes metformin(Drug information on metformin) (2000 mg/d) for her diabetes and no medications for her lipids.

Would you consider more aggressive treatment of her elevated HbA1c? If so, why—and with what medications? What goals would you have for her A1C? Would you do anything to treat her lipids?

Click here for Dr. Shahady’s discussion of options.

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by susan kweskin | October 15, 2012 9:41 AM EDT

Dr. Shahady responds to the question by Grace Jacob:

There is no simple answer to this question -- it depends on food intake and activity. You might start out with 40% of the IV dose and increase depending on the blood sugar, food intake, etc. If the patient did not have diabetes before, once IV insulin is not needed you may start a basal insulin and gradually increase the dose depending on blood sugar levels. Alternately, you could start orals and/or a GLP-1 agonist, depending on the patient's needs and response to therapy.

by Grace Jacob | October 12, 2012 6:59 AM EDT

can someone the calculation of dosage of premixed insulin when we change over from intravenous insulin






 
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