Locoregional recurrence is fairly typical in gastric cancer, but surgical tumor removal is not an option. So researchers in China investigated the feasibility of CT-guided brachytherapy using iodine-125 seed implantation for local control of recurrent gastric cancer. In addition to achieving respectable survival and response rates, this approach had no serious complications, they report. The authors also explain how tumor size influences the complete response rate.
RESULT: Computed tomography-guided permanent brachytherapy for locoregional recurrent gastric cancer
Radiation Oncology | Jul 24, 2012 (FREE FULL TEXT)
Node-positive gastric cancer patients who undergo radiation therapy generally have better survival odds, regardless of the extent of surgical resection and lymph node dissection. That's the conclusion of an analysis of treatment outcomes in a U.S. database of over 11,000 patients. The authors of this analysis offer details on which patients gained the most benefit from radiotherapy based on their cancer stage and lymph node removal status.
RESULT: Adjuvant radiation therapy increases overall survival in node-positive gastric cancer patients with aggressive surgical resection and lymph node dissection: a SEER database analysis
American Journal of Clinical Oncology (PubMed) | Jun 1, 2012 (Free abstract. Full text $53.35)
