Topics:

Laxatives With Antraquinones Associated With Melanosis Coli

Laxatives With Antraquinones Associated With Melanosis Coli

The finding of pigmented mucosa—melanosis coli—on colonoscopy is associated with which of the following laxatives?

A. Senna
B. Docusate sodium (Colace)
C. Polyethylene glycol (Miralax)
D. Milk of magnesia

Correct answer: A

Laxatives that contain antraquinones (eg, senna) can induce a dark pigmentation in the colonic mucosa. The cecum and rectum are the most commonly affected sites. Despite its appearance on colonoscopy, melanosis coli is a benign finding. The other laxatives do not cause this condition.

 
Loading comments...

By clicking Accept, you agree to become a member of the UBM Medica Community.