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Lesinurad Combos Nail Uric Acid Targets in Phase III Trials
Unpublished results from Phase III trials of the uric acid inhibitor lesinurad offer promise of help for gout patients who have not reached treatment targets with allopurinol or febuxostat.
50-Year-Old Woman With Bilateral Knee Pain and Swelling
A month after being diagnosed with gout, this woman returned for care with pain, swelling, and effusion in both knees. Can you guess the diagnosis?
Gout and Sex: Different, and Not So Good
(EULAR 2014) New research finds erectile dysfunction common among gout patients, and distinctive differences between men and women in predisposing factors and treatment risks.
Poor Treatment Results in Gout: Unintentional Resistance?
Failure to achieve urate targets in gout may have more to do with innate resistance or under-dosing than with poor adherence to the allopurinol regimen.
Tophi Defined: Neutrophil NETS, Out of Control
What actually are the tophi of gout? They are bits of blasted neutrophils with their feedback controls out of kilter, according to new research.
New Staging System Proposed for Gout
When does gout need treatment? A new set of staging criteria hopes to clarify the answer, and a separate report warns of the risks of unjustified treatment.
Why Half of Gout Patients Don't Take Their Meds
Medication adherence among gout patients is poorer than for many other chronic conditions. Authors of a systematic review point to some probable explanations.
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