An increasing number of older AIDS patients are starting antiretroviral therapy. Maximum survival benefit is realized when ART is initiated when CD4 counts are high--regardless of the patient's age, according to a new study.
Clinically significant drug interactions involving antiretroviral agents have been reported in 30% to 40% of HIV-positive patients in the USA. However, this study finds that just a few therapeutic groups are responsible for most of the interactions detected.
Previous studies have established that early treatment of HIV dramatically reduces the odds of spreading the infection to a sexual partner. The START trial provides evidence that early therapy benefits a patient's own health.
Mental illness is a risk factor for HIV infection. It brings a number of behavioral correlates that put patients at risk for getting infected. As HIV infection worsens, it begins to affect the brain, and cyclical relationship between the disease and mental illness begins.