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Clinical News & Knowledge: Human Papillomavirus (HPV)
Continued Cytological Monitoring for Cervical Cancer Despite Prior Vaccination
The human papilloma viruses (HPVs) are among the widespread sexually transmitted pathogens infecting women. Like HIV, HPV–s More »
Establishing an Anal Dysplasia Clinic for HIV-Infected Men: Initial Experience
Hologic nabs approval for two new HPV tests
Women’s healthcare company Hologic received FDA premarket approval for Cervista HPV HR test and the Cervista HPV 16/18 test. The tests are manufactured by Third Wave Technologies. The high-risk Cervista HPV HR test has been approved to screen patients with atypical squamous cells of undetermined... More »
Landmark Study Shows HPV Testing Significantly Reduces Deaths from Cervical Cancer
Results from an 8-year trial involving more than 130,000 women published in The New England Journal of Medicine (360:1385-1394, 2009) demonstrate that in low-resource settings, a single round of human papillomavirus (HPV) testing significantly reduces the numbers of advanced cervical cancers and... More »
Sexually Transmitted Viral Infections in Women: HIV, HSV, and HPV
Over the past 15 years in the United States, HIV/AIDS has become increasingly common among women. In 1990, women made up only 11% of the newly reported cases of AIDS.1 In 2006, 27% of newly reported AIDS cases were in women.2 More »
HPV Vaccine: Questions and Controversies
The approval of Gardasil (Merck)—a recombinant vaccine providing protection against human papillomavirus (HPV)—in 2006 sparked instant controversy.1,2 Because HPV infection is a sexually transmitted disease, the use of a vaccine for such a disease brought the following political, medical, and moral... More »
HPV Infection in Men: Site-Specific Prevalence and Risk Factors
The prevalence of anal human papillomavirus (HPV) infection was 24.8% among a study population of 222 heterosexual men who confirmed that they had never engaged in male-male sexual intercourse. 1 More »
Effect of Patient Adherence to Antiretroviral Therapy on the Progression of Cervical Dysplasia Among HIV-Infected Women
A case-control study was conducted that involved a retrospective chart review of 181 HIV-infected women in whom cervical dysplasia had been diagnosed to examine the association between patient adherence to highly active antiretroviral therapy and the regression or stabilization of cervical... More »
HPV-Linked Oral Cancer: Another Argument for Universal HPV Vaccination of Boys and Girls

Five years ago, the International Agency for Research on Cancer (IARC) conducted a case-control study in 9 sites (Italy, Spain, Northern Ireland, Poland, India, Cuba, Canada, Australia, and Sudan) of 1415 participants with cancer of the oral cavity and 255 with oropharyngeal carcinoma.1 Markers... More »

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