Nervous System Diseases

Amyotrophic Lateral Sclerosis in a Young Man

The neurodegeneration of ALS is relentlessly progressive and presently incurable. Only one medication has been shown to extend life. Here, a case study, including videos.

Nervous System Diseases

Deep brain stimulation, stem cell treatment, studying mitochondria—to mark Parkinson’s Awareness Month, we review some noteworthy new concepts.


The SPG is a promising target for migraine treatment, but robust evidence of efficacy for routine use of noninvasive device–mediated SPG blockade is needed.


A new way to treat dementia and other diagnosis and treatment developments are in the news.

A switch to a second-line drug in a patient receiving first-line therapies likely will be effective at decreasing disease activity.

There’s a new app for tracking symptoms of Parkinson disease, Alzheimer and Parkinson diseases may share characteristics with mad cow disease, and a skin test may one day be used to detect both AD and PD.

While a majority of persons with the 4 most common cancers are told the diagnosis, fewer than half of persons with AD get that kind of information. This could be a problem.

An FDA-approved drug for high blood pressure alleviates clinical symptoms of MS in mice, showing great promise for humans.


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