The lesion seen here, caused by HPV-16, is a papillary squamous cell carcinoma in situ. HPV-16 is highly associated with this orophayrngeal cancer and premalignant diseases.1-3 It is currently the primary cause of oral cancer in men.
Photo courtesy of Dr Dolphine Oda.
References
1. Chaturvedi AK, Engels EA, Pfeiffer RM, et al. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol. 2011;29:4294-4301.
2. James SD. Oral sex linked to rise in men’s throat cancer. ABC News. October 20, 2010. http://abcnews.go.com/Health/ReproductiveHealth/hpv-oral-cancers-rise-oral-sex-popular-spread/story?id=11916068#.T891Lb9XsmI. Accessed June 6, 2012.
3. Syrjänen S, Lodi G, von Bültzingslöwen I, et al. Human papillomaviruses in oral carcinoma and potentially malignant disorders: a systematic review. Oral Dis. 2011;17(suppl 1):58-72.
References
1. Chaturvedi AK, Engels EA, Pfeiffer RM, et al. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol. 2011;29:4294-4301.
2. James SD. Oral sex linked to rise in men’s throat cancer. ABC News. October 20, 2010. http://abcnews.go.com/Health/ReproductiveHealth/hpv-oral-cancers-rise-oral-sex-popular-spread/story?id=11916068#.T891Lb9XsmI. Accessed June 6, 2012.
3. Syrjänen S, Lodi G, von Bültzingslöwen I, et al. Human papillomaviruses in oral carcinoma and potentially malignant disorders: a systematic review. Oral Dis. 2011;17(suppl 1):58-72.
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