A15-year-old girl was referred to a pediatric endocrinologist for evaluation of hyperthyroidism. Her primary concerns were intermittent increases in heart rate and appetite (with a weight gain of 7 kg within the past year), feeling hot at night even in winter, persistent lower extremity edema that had been present since age 4 years, and difficulty in concentrating. She denied having diarrhea, sweating, fatigue, breathing difficulties, hair loss, or changes in hair texture.
For 3 days, a 7-year-old girl had severe, generalized abdominal pain. The patient described the pain as sharp and achy without radiation; she denied any relieving or aggravating factors. She also reported decreased appetite and energy for the past week.
The rash on this 4-week-old girl had appeared 5 days earlier on her face as thickened scales on an erythematous base and subsequently spread to the scalp, shoulder, chest, abdomen, and extremities. A few bullae were noted on the neck and hands. Initial treatment with cephalexin failed to control the rash, and the infant was admitted to the hospital for further evaluation.
A 9-year-old previously healthy boy presents to his pediatrician with acute onset of a nonproductive cough, left eye swelling without loss of visual acuity, persistent fever of 3 days’ duration, chills, headache, chest pain, vomiting, and left knee pain with inability to bear weight. More »
A 65-year-old man, who was lost to follow-up after abdominal-perineal resection for rectal adenocarcinoma 9 months earlier, presents with progressively worsening neurological symptoms, including bilateral hearing loss, dizziness, gait disturbance, ataxia, and blindness in the right eye. More »
Most children who present with undifferentiated rash and fever—or fever and rash and nonspecific physical findings—have a benign viral illness. However, identifying those few who have an early or atypical presentation of a more serious disease is vitally important. Here—clues that can help. More »
Remission must be the ultimate therapeutic goal for patients with rheumatoid arthritis (RA), according to an international task force that set out to develop recommendations for achieving optimal outcomes in RA in clinical practice. Treatment targets have helped improve outcomes in other areas of... More »
Separate patterns of comorbidity are identified in patients who have fibromyalgia syndrome (FMS), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and noninflammatory rheumatic disorders (NIRD). The patterns include the type of comorbid variables reported and their associations with... More »
Clinical study findings of recent years support the notion that patients with rheumatoid arthritis (RA) should be treated earlier and more aggressively. Monotherapy with disease-modifying antirheumatic drugs (DMARDs) is effective in some cases, but triple DMARD therapy is superior to double therapy... More »
Acute rheumatic fever (ARF) was a major cause of morbidity and mortality in past decades, but with the passage of time and medical advances, it faded from the forefront of clinical medicine and, in turn, from physicians' minds. However, a resurgence of ARF has been reported in the United States and... More »
Children who present with rash and fever can be divided into 3 groups: those with features of serious illness who require immediate intervention, those with clearly recognizable viral syndromes, and those with early or undifferentiated rash. The morphology of lesions among children with symptoms of... More »
journal for health professionals and researchers in the rheumatic diseases ... An association between rheumatoid factor (RF) and increased mortality ... been described in individuals with rheumatoid arthritis. The objective ...
journal for health professionals and researchers in the rheumatic diseases ... Criteria for the classification of rheumatoid arthritis: a game changer ... Annals of the Rheumatic Diseases and Arthritis Care & Research ... clinical trials of patients with rheumatoid arthritis (RA). ...
journal for health professionals and researchers in the rheumatic diseases ... Concise report Demyelinating events in rheumatoid arthritis after drug exposures Sasha ... risk of demyelinating events in rheumatoid arthritis (RA). ...
journal for health professionals and researchers in the rheumatic diseases ... Assessment of hand bone loss in rheumatoid arthritis by high-resolution peripheral ... was evaluated in patients with rheumatoid arthritis (RA) ...
journal for health professionals and researchers in the rheumatic diseases ... Increased prevalence of diastolic dysfunction in rheumatoid arthritis Kimberly P Liang1 ... diastolic dysfunction in subjects with and without rheumatoid arthritis (RA) ...
reoperation and late mortality in patients undergoing tricuspid valve repair for rheumatic disease. METHODS: Between 1997 and 2007 299 consecutive patients ... underwent surgical repair of the tricuspid valve for multivalvular organic rheumatic disease. A total of 184 patients was found ...
occur after operative procedures. CASE: A patient with rheumatoid arthritis presented with vaginal discharge and bleeding with ulcerative red ... Cervical biopsy was highly suggestive of rheumatoid nodules. This prompted revision of the diagnosis of tuberculosis ...
M?ori continue to be unacceptably high. The impact of rheumatic heart disease is inequitable on these populations as compared ... The associated cardiac morbidity including the development of rheumatic valve disease and cardiomyopathy with possible sequelae of heart failure ...
1/2 in left or right atrial tissue from patients with rheumatic valvular disease with or without atrial fibrillation. METHODS: Atrial tissue samples were obtained from 39 patients with rheumatic mitral valve disease during cardiac surgery. ...
common than their left-sided counterparts. Furthermore whilst organic rheumatic involvement of the tricuspid valve is not uncommon it receives ... carried out to assess the epidemiology diagnosis and management of organic rheumatic tricuspid valve disease (RTVD) over the past half century. ...
Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently clear and consensual international recommendations on RA treatment ...
Recommendations were added to the U.S. guidance for women with rheumatoid arthritis history of bariatric surgery peripartum cardiomyopathy endometrial hyperplasia inflammatory ...
A15-year-old girl was referred to a pediatric endocrinologist for evaluation of hyperthyroidism. Her primary concerns were intermittent increases in heart rate and appetite (with a weight gain of 7 kg within the past year), feeling hot at night even in winter, persistent lower extremity edema that had been present since age 4 years, and difficulty in concentrating. She denied having diarrhea, sweating, fatigue, breathing difficulties, hair loss, or changes in hair texture.
For 3 days, a 7-year-old girl had severe, generalized abdominal pain. The patient described the pain as sharp and achy without radiation; she denied any relieving or aggravating factors. She also reported decreased appetite and energy for the past week.
The rash on this 4-week-old girl had appeared 5 days earlier on her face as thickened scales on an erythematous base and subsequently spread to the scalp, shoulder, chest, abdomen, and extremities. A few bullae were noted on the neck and hands. Initial treatment with cephalexin failed to control the rash, and the infant was admitted to the hospital for further evaluation.
