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Rheumatic Diseases

Rheumatic Diseases

Here: a primary care perspective on diagnosis of -- and care of patients with -- rheumatologic disorders.

Rheumatic Diseases

A 71-year-old woman with one month of joint pain showed a classic sign of eosinophilic fasciitis.

A comparative study finds the severity of xerostomia (oral dryness) in Sjögren syndrome a good indicator of other serious problems, including fatigue, anxiety, and cardiovascular symptoms.

A rare vasculitis that is fatal in adolescence turns out to be caused by a mutation in interferon that affects the JAK pathway. This has implications for other auto-inflammatory diseases including lupus.

In a 120-patient randomized trial, hydroxychloroquine was no better than placebo at relieving the dryness, pain, and fatigue of Sjögren syndrome.

Why is celiac disease so much more common in Sweden than in the US? A study compares differences in genes and environment, presenting this riddle as a model for other autoimmune disorders.

A 5-year-old boy had pain and weakness in his legs and had trouble climbing stairs. He had a dramatic rise in CPK followed by erythematous papules on the hands, as shown, and a rash around the eyelids. Which diagnosis is most likely?

hepatitis

A small case series suggests that the mTOR inhibitor sirolimus has fewer adverse events and similar efficacy to other options for steroid-refractory hepatitis.

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