Improving on Predictors of Osteoporotic Fracture

FEATURED SEARCH TERM:   osteoporosis treatment



The fracture risk assessment system (FRAX) can accurately predict the 10-year fracture risk in women currently or previously treated for osteoporosis, according to this large, retrospective study of population-based databases. However, it may overestimate the probability of hip fracture in long-term bisphosphonate users. Nevertheless, FRAX still has value for guiding continued treatment or treatment withdrawal, suggest the authors of the report below.


RESULT: Does osteoporosis therapy invalidate FRAX for fracture prediction?
Journal of Bone and Mineral Research | June 1, 2012 (FREE FULL TEXT)


Updated versions of two QFracture algorithms show improved performance in predicting the risk of osteoporotic and hip fractures, according to this large British prospective, cohort study. The new-and-improved algorithms, which include a wide range of additional clinical variables, now can help primary care physicians test patients who are older than 85.


 
RESULT: Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study
British Medical Journal | May 22, 2012 (FREE FULL TEXT)