Linda Stein Gold, MD

Key Takeaways on the Role of Oral JAK Inhibitors in Atopic Dermatitis Management

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What are some key takeaways or advice for other dermatologists treating patients with atopic dermatitis with JAK inhibitors?

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Experts discuss key takeaways for dermatologists managing atopic dermatitis with JAK inhibitors, emphasizing the importance of individualized treatment plans, monitoring for safety and efficacy, and balancing the benefits of JAK inhibitors with potential risks, especially in long-term use.

Oral JAK Inhibitor Dose Escalation in Atopic Dermatitis Treatment

With JAK inhibitor therapy, the dose can be increased if needed based on clinical judgment. How do you decide when a patient should increase the dose of their JAK inhibitor?

How often do you increase to the higher dose of JAK inhibitors in practice?

Experts discuss how clinical judgment guides the decision to increase the dose of a JAK inhibitor, considering factors like patient response and symptom severity, and how often dose escalation is implemented in practice based on individual patient needs.

Addressing Treatment Response and Switching Among Systemic Therapies in Atopic Dermatitis

Several studies have shown that patients who have not responded to biologic therapy can achieve improved results when switching to a JAK inhibitor. How do these data impact your clinical practice and your threshold for switching systemic therapies for patients?

Experts discuss how data from studies like JADE EXTEND, Heads Up Extension, and LEVEL UP, showing improved outcomes with JAK inhibitors in patients who failed biologic therapy, influence their clinical practice and decision-making when considering switching systemic therapies for patients with atopic dermatitis.

Utilizing Patient Factors to Guide Treatment Selection in Atopic Dermatitis

What are some circumstances where you would prescribe an oral JAK inhibitor for moderate to severe AD initially over a biologic?

What advantages might a JAK inhibitor have over a biologic?

Experts discuss situations where an oral JAK inhibitor might be prescribed initially over a biologic for moderate to severe atopic dermatitis (AD), noting advantages such as oral administration, quicker onset of action, and convenience, which may make it a preferred option for some patients.

Linda Stein Gold, MD

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