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July 01, 2022
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With guselkumab, patients with active psoriatic arthritis achieved efficacy that was sustained through a 2 year clinical trial. Results show that the treatment offered continuous improvement across measures of health-related quality of life.
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Women with the highest PTSD symptoms level experienced significantly worse rates of change regarding learning and working memory.
Event rates were inversely proportional to kidney function in patients with chronic coronary disease.
Tenofovir was linked to a decreased incidence rate of HCC compared to entecavir. However, this difference was not considered statistically significant.
June 30, 2022
According to the results, individuals with SCT who previously had COVID-19 also had various preexisting kidney conditions that were associated with poor outcomes.
A substantial number of individuals (nearly 40%) reached arterial stenosis of at least 50%, according to the findings.
The majority of patients in the phase 2 study met the primary efficacy endpoint of a greater than or equal to a 10% reduction in total stool output over the 6-week efficacy evaluation period.
The increase was highest for Hispanic and non-Hispanic Black Women.
Despite an increased risk of new-onset psoriasis from TNFi treatment, investigators considered the absolute risk to be “modest”, with 241 patient-years of exposure needed for 1 additional event.
Varenicline was efficacious at weeks 12, 24, and 52 of the trial compared with placebo in a smoking cessation program.