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Nephrology

The HCPLive nephrology page is a resource for medical news and expert insights on kidney disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments in nephrology, and more.

IgA nephropathy advanced in 2025 with FDA approvals, positive phase 3 trials, and growing disease-modifying therapies


IgA Nephropathy in 2025: Year in Review

In 2025, FDA approvals, pivotal trials, and emerging therapies shifted nephrology care toward precision and mechanism-driven kidney medicine.


Nephrology in 2025: Year in Review

Findings from a retrospective observational cohort study indicate podometrics may inform a less invasive treatment approach in IgA nephropathy (IgAN).


Podometrics Could Guide IgAN Treatment While Reducing Invasiveness

A retrospective cohort study developed and validated a predictive model for IgA nephropathy, using routinely available variables. 


IgA Nephropathy Prediction Model Aids 5-Year Survival Estimation

A retrospective cohort in finerenone showed nearly 40% proteinuria reduction at 8 months and stable eGFR in patients with IgA nephropathy.


Finerenone Shows Promise in IgAN: Reduced Proteinuria, Stable Kidney Function 

Key FDA approvals, pivotal IgAN and glomerular trial results, and transplant and CKD insights from November 2025.


8 Nephrology Headlines You Missed in November 2025

The phase 2 study of ALXN2050 in IgAN did not meet its proteinuria endpoint, with emerging safety concerns and early termination.


Factor D Inhibition Lacks Efficacy For IgAN in Phase 2 ALXN2050 Trial, With Sayna Norouzi, MD 

FDA grants accelerated approval for sibeprenlimab for reducing proteinuria in IgA nephropathy.

FDA Awards Accelerated Approval to Sibeprenlimab in IgA Nephropathy 

Pediatric IgA nephropathy shows slow progression, high remission rates, and frequent relapse, with new risk factors identified to improve long-term prognosis and management.


New Evidence on Pediatric IgAN Progression Supports Need for Extended Follow-Up

A curated recap of 8 impactful trial updates from the American Society of Nephrology Kidney Week 2025.

Kidney Week 2025 Recap: 8 Trial Updates to Know in Nephrology

The HCPLive Berger disease page is a resource for medical news and expert insights on IgA nephropathy. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments in Berger disease, and more.