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FDA grants Priority Review to Agios’ mitapivat sNDA for sickle cell disease, with a PDUFA date set for November 1, 2026.

FDA Grants Priority Review to Agios’ Mitapivat sNDA for Sickle Cell Disease

Exagamglogene autotemcel (Casgevy) is now the first CRISPR-based gene-editing therapy to reach this age group in either condition.

FDA Expands Exa-Cel Gene Therapy Approval to Children 2 Years and Up With SCD or β-Thalassemia

Stay updated with the latest healthcare breakthroughs, including FDA submissions and new cardiology guidelines.

The HCPFive: Top News for Healthcare Providers from the Week of 05/10

Catch up on the hematology news and data you missed from April 2026. 

4 Hematology Headlines You Missed in April 2026

Inusa discusses how clinicians can close gaps in sickle cell disease care and global disparities. 

Using SWAY’s Global Sickle Cell Data to Close Access, Treatment Gaps 

Study investigator Inusa explains the gap in sickle cell disease findings from SWAP, a multinational survey. 

Increased Sickle Cell Pain Burden in Sub-Saharan Africa Despite Younger Patients

Stay updated with the latest healthcare breakthroughs, including FDA actions and new topline clinical trial data, in this week’s essential news roundup.

The HCPFive: Top News for Healthcare Providers from the Week of 04/19

Hanna explains the real-world barriers to implementing gene editing therapies in sickle cell disease. 

First-Generation Gene Editing in Sickle Cell Faces Real-World Limits Despite Breakthrough Results

Etavopivat reduced VOC events by 27% and improved hemoglobin response in the phase 3 HIBISCUS trial in sickle cell disease.

Phase 3 HIBISCUS: Etavopivat Cuts VOC Events, Improves Hemoglobin in SCD

Hanna describes the "freedom" patients with sickle cell disease reported after being treated with reni-cel, a one-time edited gene therapy. 

One-Time Gene-Editing Therapy Gives Patients “Freedom” From Pain Crisis

Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria Condition Center page, visitors can find resources on the topics of medical news and expert insight into PNH. Content includes articles, interviews, videos, podcasts, and breaking news on PNH research, treatment, and drug development.

Anemia

Sickle Cell

Sickle Cell condition center page, resources on the topics of medical news and expert insight into sickle cell disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on sickle cell research, treatment, and drug development.