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Rheumatology

Rheumatology condition center page is a comprehensive resource for clinical news and insights on rheumatologic disease. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for arthritis, gout, nr-AxSpA, and more.

In a phase 3 trial, the first-in-class triple agonist delivered up to an average of 71.2 lbs weight loss and reduced WOMAC pain scores for knee osteoarthritis.

TRIUMPH-4: Retatrutide Delivers Weight Loss, Knee Osteoarthritis Pain Relief

A compilation of 13 trials presented as late-breaking data at ACR Convergence 2025.

ACR Convergence 2025 Recap: Late-Breaking Trials to Know

Khasru discussed the potential of adMSCs to improve outcomes in knee osteoarthritis.

Adipose-Derived MSCs Show Promise as Nonsurgical Option for Knee OA, With Moshiur Rahman Khasru, MBBS, MSc

Conaghan discussed the potential of StEPP as a measure in clinical trials.

Objectively Measuring Pain and Function in Osteoarthritis, With Philip Conaghan, MBBS, PhD

Conaghan discussed the potential of LEVI-04 for knee osteoarthritis at ACR 2025.

LEVI-04 Improves Pain, Function in Knee Osteoarthritis, with Philip Conaghan, MBBS, PhD

Conaghan discussed findings from the ENX-CL-05-001 phase 2a trial at the ACR Convergence.

Apoptotic Cell Therapy Shows Promising Benefits for Older Adults With Knee OA, with Philip Conaghan, MBBS, PhD

Targeting changes in foot progression angle to maximally reduce knee loading led to greater reductions in medial knee pain and knee adduction moment peak.

Personalized Walking Pattern May Reduce Knee Osteoarthritis Symptoms, Delay Progression

However, a significant effect was seen in a subgroup of participants with severe pain (VAS score ≥ 80 mm) at baseline.

Methotrexate Not Seen to Have Effect in Knee Osteoarthritis Pain or Effusion-Synovitis

New research highlights the importance of lifestyle changes to combat knee osteoarthritis, revealing obesity and knee injuries as key risk factors.

Obesity, Previous Injury, Occupational Physical Activity Are Key Drivers of Knee Osteoarthritis

Conaghan discussed findings from a phase 2 trial at the ACR 2024 Convergence.

Philip Conaghan, MBBS, PhD: Investigating NT3 Inhibition for Improving Osteoarthritis

On the HCPLive osteoarthritis page, resources on the topics of medical news and expert insight into OA can be found. Content includes articles, interviews, videos, podcasts, and breaking news on degenerative joint disease, and more.