Quick Facts about Niemann-Pick Disease
- The disease refers to a group of disorders: Type A, B, C1, and C2.
- Type A is the most severe form; Type C is the most common.
- Lipids may accumulate in the brain, spleen, liver, lungs, and bone marrow.
- It is autosomal recessive.
- The manifestations are diverse; a host of neurological symptoms may occur.
- Patients may develop NP, especially NPC, any time in their life. However, the disease usually manifests early in life.
- The disease is panethnic but has a higher rate among populations with greater consanguinity.
- There is no cure for this disease.