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Until this decision, clinicians relied on off-label, interferon-based regimens with limited efficacy.

Bulevirtide Receives Historic First FDA Approval for Chronic Hepatitis Delta

GI and liver safety signals for clinicians to know from the VISTAS evaluating volixibat in PSC-associated pruritus.

Volixibat's Safety Profile Explained for PSC, With Kris Kowdley

Kowdley explains phase 2b VISTAS data suggesting volixibat rapidly reduced PSC-associated pruritus in adults with limited treatment options.

Volixibat Shows Rapid Itch Relief in PSC in Phase 2b VISTAS, With Kris Kowdley, MD

Lee discusess DDW 2026 data linking binge drinking frequency to advanced hepatic fibrosis in SLD. 

Binge Drinking Frequency Tied to Advanced Fibrosis in MetALD, ALD, With Frances Lee, MD

Noureddin discusses HU6’s mitochondrial uncoupling mechanism and why muscle preservation may become increasingly important in MASH care.

Oral HU6 Shows Fat-Selective Weight Loss in MASH, With Mazen Noureddin, MD

Catch up on updates in viral hepatitis treatment, advances in rare liver disease care, and more.

5 Hepatology Headlines You Missed in April 2026

COBRA findings suggest 1 day of antibiotic treatment is preferred in acute cholangitis after adequate biliary drainage compared to longer guidelines.


Shorter Antibiotic Treatment After Adequate Biliary Drainage Non-Inferior in Acute Cholangitis

Volixibat reduced cholestatic pruritus in phase 2b primary sclerosing cholangitis data, with diarrhea and liver test elevations reported.

Volixibat Improves Pruritus in Phase 2b PSC Trial

New paired biopsy data show histologic regression after metabolic bariatric surgery in compensated MASH patients, challenging the irreversibility of cirrhosis.

Histologic Evidence of MASH Cirrhosis Regression After Metabolic Bariatric Surgery, With Sobia Laique, MD

Njei explains the evolving treatment landscape for MASLD and how it impacts the cost-effectiveness of noninvasive tests for screening.

Optimizing MASLD Screening in the Era of Liver-Directed Therapy, With Basile Njei, MD, PhD, MPH

Alpha-1 antitrypsin deficiency

Cholangitis

cholangitis page, resources on the topics of medical news and expert insight into cholangitis can be found. Content includes articles, interviews, videos, podcasts, and breaking news on research, treatment, and drug development in PBC, PSC, and more!

MASH / MASLD

The HCPLive MASH & MASLD page is a comprehensive resource for clinical news and insights on metabolic dysfunction-associated steatotic liver disease and steatohepatitis. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for fatty liver disease, steatohepatitis, and more.

Hepatitis C

Hepatitis C page, resources on the topics of medical news and expert insight into HCV can be found. Content includes articles, interviews, videos, podcasts, and breaking news on hepatitis C virus research, treatment, and drug development.