Clinical Perspectives on Aprocitentan for Hypertension

Summary for Physicians

Experience With Aprocitentan in Clinical Practice

Aprocitentan is increasingly used in clinical practice for managing resistant hypertension. Its effectiveness in lowering blood pressure, especially in patients who have not responded well to other treatments, makes it a valuable option.

Patient Selection Criteria for Aprocitentan

Criteria: Aprocitentan is often considered for patients with uncontrolled hypertension despite using a 3-drug regimen, especially in those with additional comorbidities like diabetes or chronic kidney disease.

Best Responders: Patients who are more likely to respond well to aprocitentan include those with high baseline blood pressure levels and a history of resistant hypertension.