Emerging Treatment Options in Patients With Difficult-to-Treat Hypertension - Episode 20
A panelist discusses how aprocitentan is most beneficial for patients who have tried multiple antihypertensive medications without success, particularly those with chronic kidney disease, abnormal kidney function, or hyperkalemia who cannot tolerate other medication classes that affect electrolyte levels.
Ideal Candidates for New Therapy
The ideal candidates for aprocitentan are patients who have tried multiple antihypertensive medications without achieving blood pressure control. This medication provides an additional class option, particularly beneficial for those with abnormal kidney function or problems with hyperkalemia (elevated potassium levels).
Patients with resistant hypertension complicated by chronic kidney disease who cannot tolerate other medication classes that affect kidney function or electrolyte levels should be strongly considered for aprocitentan therapy. The medication provides a viable alternative when traditional options are contraindicated.
Every medical practice encounters patients who exhibit intolerance to standard blood pressure medications. In these challenging cases, aprocitentan offers another therapeutic option to try when other approaches have failed due to side effects or intolerability.