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Chronic Hand Eczema: Clinical Insights, Patient Experience, and Emerging Therapeutics - Episode 6

Current Treatments Options for Patients With CHE

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An expert discusses how chronic hand eczema (CHE) treatment follows a stepwise approach from general care and barrier protection to topical therapies (corticosteroids and calcineurin inhibitors) and systemic options (alitretinoin, immunosuppressives, and newer biologics for atopic dermatitis).

Video content above is prompted by the following:

CHE Treatment Approaches

Key Themes:

  • Treatment hierarchy: Baseline care (barrier protection, moisturization, and trigger avoidance), topical therapies, and systemic options.
  • Topical treatments: Corticosteroids and calcineurin inhibitors show efficacy but have limitations for long-term use.
  • Systemic options: Traditional immunosuppressants carry significant safety concerns, while newer targeted therapies for atopic dermatitis have been repurposed for CHE.

Notable Insights:

Dr Chovatiya discussed complications of long-term topical steroid use, including "skin thinning, loss of subcutaneous fat, potential systemic absorption, and even permanent depigmentation," emphasizing the need for better treatment options.

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