Generalized Pustular Psoriasis: Recognizing Signs, Symptoms, and Its Impact on Patients - Episode 3

Flare-Ups and Episodic Nature of Generalized Pustular Psoriasis (GPP)

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A patient and dermatologists discuss flare-ups and episodic nature of generalized pustular psoriasis (GPP).

This is a video synopsis/summary of a panel discussion involving Tina Bhutani, MD; J. Scott Boswell, MD; and Kanya Oul, RN.

In the discussion, Kanya, the patient, shares her experience with generalized pustular psoriasis (GPP) before receiving stable treatment, highlighting the frequency and severity of her flare-ups. She recounts how she was frequently hospitalized every 2 to 3 years during childhood due to major flare-ups, often experiencing symptoms like fever, malaise, and extreme fatigue. However, she struggled to maintain clear skin in between flare-ups, always having patches and ongoing issues.

Kanya also describes the challenges of finding effective treatment, including a period where she was hospitalized for a month in the pediatric ICU (intensive care unit) due to illness. Despite attempts with systemic steroids like prednisone, she experienced rebound effects and sought alternative treatments, which sometimes exacerbated her condition.

The conversation delves into triggers for GPP flare-ups, including the withdrawal of systemic steroids, infections, stress, and even pregnancy, which can induce flare-ups in contrast to plaque psoriasis. Kanya emphasizes the importance of recognizing symptoms indicating a flare-up's onset, such as internal inflammation and irritation.

Through collaboration with her dermatologist, Kanya has developed a system to manage her condition, promptly switching medications when necessary to control symptoms and maintain clear skin in between flare-ups. This highlights the ongoing challenges of managing GPP and the importance of individualized treatment plans tailored to each patient's needs.

Video synopsis is AI-generated and reviewed by HCPLive editorial staff.