Navigating Therapeutic Pathways and Transforming Care in ATTR-CM - Episode 3
The panel explores strategies to improve collaboration across specialties to accelerate diagnosis of ATTR-CM. They note that while clinicians who frequently treat cardiac amyloidosis easily recognize red flags, most patients initially present in orthopedic, neurology, or primary care settings where awareness may be limited. The group emphasizes the importance of education rather than universal screening: common conditions like bilateral carpal tunnel syndrome are widespread, and only a minority will be linked to amyloid. Instead, these findings should be viewed as risk factors that prompt thoughtful clinical review rather than routine tissue sampling. Effective models of care involve strengthening communication channels between specialists and building workflows that encourage referral when constellation patterns emerge. Advanced practice providers often serve as key connectors, helping evaluate history, coordinate testing, and reinforce awareness. The panel highlights that integrating these teams can enable earlier identification, reduce missed opportunities, and help patients access disease-modifying therapies before significant cardiac decline occurs.
The panel explores strategies to improve collaboration across specialties to accelerate diagnosis of ATTR-CM. They note that while clinicians who frequently treat cardiac amyloidosis easily recognize red flags, most patients initially present in orthopedic, neurology, or primary care settings where awareness may be limited. The group emphasizes the importance of education rather than universal screening: common conditions like bilateral carpal tunnel syndrome are widespread, and only a minority will be linked to amyloid. Instead, these findings should be viewed as risk factors that prompt thoughtful clinical review rather than routine tissue sampling.
Effective models of care involve strengthening communication channels between specialists and building workflows that encourage referral when constellation patterns emerge. Advanced practice providers often serve as key connectors, helping evaluate history, coordinate testing, and reinforce awareness. The panel highlights that integrating these teams can enable earlier identification, reduce missed opportunities, and help patients access disease-modifying therapies before significant cardiac decline occurs.