Experts discuss how the clinical presentation of hypercortisolism differs in the primary care vs specialist setting, highlighting earlier signs/symptoms vs overt disease, and review recent data on the prevalence of hypercortisolism, including its higher occurrence in patients with difficult-to-control diabetes, difficult-to-control hypertension, and cardiovascular disease.
How would the clinical presentation of hypercortisolism differ in the primary care vs specialist setting?
Earlier signs/symptoms vs overt disease
The prevalence of hypercortisolism in certain at-risk patients is higher than previously thought. Can you discuss some of the recent data on hypercortisolism prevalence?
Prevalence of hypercortisolism in patients with difficult-to-control diabetes was 24%.
Prevalence of hypercortisolism in patients with difficult-to-control diabetes and difficult-to-control hypertension was 40%.
Patients with cardiovascular disease had a higher prevalence of hypercortisolism than those without (33.3% vs 20.9%).